Basic Information
VIS ID
TVIS44001085
Fusion event
HTLV-1-chr1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
p22.3
Reference genome
GRCh37/hg19
Start
88290223/87824540 (Hg38)
End
88290223/87824540 (Hg38)
Orient
-
Location type
Intergenic
Fragile sites / regions
FRA1D
Nearest miRNA
hsa-mir-101-1/Upstream/1466853; hsa-mir-11399/Downstream/6022292;
Nearest TSS
ENST00000473358/Upstream/452885; ENST00000436111/Downstream/81174;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/488991, chr1-CpG: 63/Downstream/638060
Nearby gene
LINC01364(No orient, 452885)
Upstream sequence
AAGATGTAGCCTGAGCTACATTCAGGTTATTTCTGAGCGACTATTGCCTGAAATGCAAAACAATCCATTCCTGTAGGGCCAGGACTATGTCCTGGGCAAT
Downstream sequence
GTGGGCATATTGTTTGTATGCAAATCTGGTTAGGGCATTTATTCTCCGTGGACTATAGCTTTGATGTGGCAAGTCAGAAGGGCTGAGGAGTTGCCCTTCT
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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