Basic Information
VIS ID
TVIS44001088
Fusion event
HTLV-1-CCDC7 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr10
Cytoband
p11.22
Reference genome
GRCh37/hg19
Start
33146061/32857133 (Hg38)
End
33146061/32857133 (Hg38)
Orient
-
Location type
Intronic
Target gene
CCDC7
Nearest miRNA
hsa-mir-1265/Upstream/2488468; hsa-mir-107/Downstream/2222465;
Nearest TSS
ENST00000439456/Upstream/171114; ENST00000450890/Downstream/32178;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/509406, chr10-CpG: 166/Downstream/100210
Upstream sequence
tgcctctggcctgtgtcaggctcaacaccaagagagatgccctcaggtaaatctactactatggggtaactagaacagaaggatctttaaagtcctttac
Downstream sequence
actgagaaATGgactccactactgtgcctacccagaatgagagccactgcactttgcccaactaatacctgcagacaatatctgcaggtgacagtctccc
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
Curate