Basic Information
VIS ID
TVIS44001096
Fusion event
HTLV-1-chr14 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr14
Cytoband
q12
Reference genome
GRCh37/hg19
Start
27330370/26861164 (Hg38)
End
27330370/26861164 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-208a/Upstream/2717599; hsa-mir-1185-1/Downstream/47478;
Nearest TSS
ENST00000550708/Upstream/17712; ENST00000552926/Downstream/11969;
Nearest CpG islands
None/Target, chr14-CpG: 35/Upstream/655892, chr14-CpG: 203/Downstream/1904519
Nearby gene
MIR4307HG(No orient, 11969)
Upstream sequence
GAGGCTATTTTACTGACAGAGTTATAGGATGGATGCAAATGAGAACAAATTTTGTATTTGCTATGGACAGATATTTGAGAATGATGAATCATAGAACATT
Downstream sequence
AATTAAGTAAAGCAATGGGACTCAAAAGAAATGGGAATTTCAGAGAGAAATGAACAGATATGTGTGGTTCCCTGGGCTCTTCTGCTTTGTTATGGTGGCT
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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