Basic Information
VIS ID
TVIS44001106
Fusion event
HTLV-1-MIR548AU integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
q12.3
Reference genome
GRCh37/hg19
Start
107946951/107330495 (Hg38)
End
107946951/107330495 (Hg38)
Orient
-
Location type
ncRNA_intronic
Fragile sites / regions
FRA2S
Target gene
MIR548AU
Nearest miRNA
hsa-mir-1285-2/Upstream/4898129; hsa-mir-10b/Downstream/1810995;
Nearest TSS
ENST00000437798/Upstream/443387; ENST00000443833/Downstream/31787;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/442735, chr2-CpG: 16/Downstream/213750
Upstream sequence
atccatgacccaggtaatgaacatagtgcccataggtcattttctaccccttgcccttcccccatctgttggtcttcggtgtctgtcattcccaccttta
Downstream sequence
tgtccatgtgtactcaatgtttagctcacacttatcagtgagaccatatggtatttTCTAccccttgctcttcccccatctggtggtctccagtgtctat
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
Curate