Basic Information
VIS ID
TVIS44001115
Fusion event
HTLV-1-chr6 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr6
Cytoband
p21.33
Reference genome
GRCh37/hg19
Start
30565113/30597336 (Hg38)
End
30565113/30597336 (Hg38)
Orient
-
Location type
Intergenic
Fragile sites / regions
FRA6H
Nearest miRNA
hsa-mir-3143/Upstream/12919; hsa-mir-10398/Downstream/293547;
Nearest TSS
ENST00000381078/Upstream/7907; ENST00000492316/Downstream/6876;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/25626, chr6-CpG: 57/Downstream/19772
Nearby gene
PPP1R10(-3064) ;
Nearest cancer related gene
PPP1R10(OG, -3064) ;
Upstream sequence
TAAATGGAAGCAGAAAGAGACACAAAGTTGTGACCACTAGGTTGTGACATGTTTGGGTTTTTTCACTTGAGCTGTATACTTCTTTGGTATTTCACGCCCT
Downstream sequence
AGCCTGGTCCTTAGATTATGTCTTCTCAGGTCTTCTCCCAGTGCACACAGCAACAACAGACTGACCTGAACACCTCCGCCCACACACACCAAGCCTGGGC
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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