VISDB Viral Integration Site DataBase

VIS ID

TVIS44001117

Fusion event

HTLV-1-E2F3 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

Adult T-cell leukemia (ATL)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr6

Cytoband

p22.3

Reference genome

Start

End

20434789/20434558 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-195-5p ; hsa-mir-34c-5p ; hsa-mir-34a-5p ; hsa-mir-210-3p ; hsa-mir-128-3p ; hsa-mir-125b-5p ; hsa-mir-17-5p ; hsa-mir-20a-5p ; hsa-mir-106b-5p ; hsa-mir-203a-3p ; hsa-mir-200b-3p ; hsa-mir-141-3p ; hsa-mir-221-3p ; hsa-mir-101-3p ; hsa-mir-32-5p ; hsa-mir-24-3p ; hsa-mir-149-5p ; hsa-mir-30c-5p ; hsa-mir-16-5p ; hsa-let-7b-5p ; hsa-mir-449a ; hsa-mir-217 ; hsa-mir-15a-5p ; hsa-mir-15b-5p ; hsa-mir-497-5p ; hsa-mir-4496 ; hsa-mir-6868-5p ; hsa-mir-3123 ; hsa-mir-3128 ; hsa-mir-3925-5p ; hsa-mir-92a-3p ; hsa-mir-92b-3p ; hsa-mir-302a-5p ; hsa-mir-449b-5p ; hsa-mir-4302 ; hsa-mir-4773 ; hsa-mir-6499-3p ; hsa-mir-6867-5p ; hsa-mir-183-3p ; hsa-mir-103b ; hsa-mir-4645-3p ; hsa-mir-4680-3p ; hsa-mir-5579-3p ; hsa-mir-93-5p ; hsa-mir-20b-5p ; hsa-mir-519d-3p ; hsa-mir-3620-3p ; hsa-mir-4715-3p ; hsa-mir-4732-3p ; hsa-mir-7849-3p ; hsa-mir-885-3p ; hsa-mir-5197-5p ; hsa-mir-224-3p ; hsa-mir-522-3p ; hsa-mir-4694-3p ; hsa-mir-100-3p ; hsa-mir-2110 ; hsa-mir-3153 ; hsa-mir-4453 ; hsa-mir-4538 ; hsa-mir-4668-5p ; hsa-mir-5093 ; hsa-mir-6124 ; hsa-mir-6733-5p ; hsa-mir-6739-5p ; hsa-mir-4272 ; hsa-mir-8065 ; hsa-mir-573 ; hsa-mir-660-5p ; hsa-mir-3616-5p ; hsa-mir-4795-5p ; hsa-mir-577 ; hsa-mir-1245b-3p ; hsa-mir-5583-3p ; hsa-mir-1233-5p ; hsa-mir-188-3p ; hsa-mir-6871-5p ; hsa-mir-145-5p ; hsa-mir-200c-3p ; hsa-mir-4314 ; hsa-mir-4642 ; hsa-mir-6780b-5p ; hsa-mir-4725-3p ; hsa-mir-4271 ; hsa-mir-6734-5p ; hsa-mir-4316 ; hsa-mir-1294 ; hsa-mir-765 ; hsa-mir-6738-5p ; hsa-mir-5194 ; hsa-mir-1914-3p ; hsa-mir-423-5p ; hsa-mir-3184-5p ; hsa-mir-1825 ; hsa-mir-4695-5p ; hsa-mir-199b-5p ; hsa-mir-199a-5p ; hsa-mir-548t-5p ; hsa-mir-548az-5p ; hsa-mir-548n ; hsa-mir-376b-3p ; hsa-mir-376a-3p ; hsa-mir-425-5p ; hsa-mir-590-5p ; hsa-mir-21-5p ; hsa-mir-32-3p ; hsa-mir-548g-3p ; hsa-mir-548av-3p ; hsa-mir-607 ; hsa-mir-3671 ; hsa-mir-3156-5p ; hsa-mir-3064-3p ; hsa-mir-3156-3p ; hsa-mir-1260b ; hsa-mir-1260a ; hsa-mir-548au-3p ; hsa-mir-5588-5p ; hsa-mir-4720-5p ; hsa-mir-4799-3p ; hsa-mir-4778-5p ; hsa-mir-26a-1-3p ; hsa-mir-200c-5p ; hsa-mir-377-3p ; hsa-mir-128-1-5p ; hsa-mir-125a-5p ; hsa-mir-503-5p ; hsa-mir-874-3p ; hsa-mir-1206 ; hsa-mir-139-3p ; hsa-mir-140-5p ; hsa-mir-203a-5p ; hsa-mir-4524a-3p ; hsa-mir-4524b-3p ; hsa-mir-490-5p

Nearest miRNA

hsa-mir-3691/Upstream/1862678; hsa-mir-10398/Downstream/6713068;

Nearest TSS

Nearest CpG islands

None/Target, chr6-CpG: 120/Upstream/31006, chr6-CpG: 131/Downstream/1152632

Nearest cancer related gene

E2F3(TSG, No orient, 0)

Upstream sequence

ATATCAAGGTGTCAGAAGAAAAATGTACAAGTAATACATCTCAGTTTCTTTTCTCCTACGCCACTTAAATCTTAGACCCACCGAAAGCTCTAAATGTATC

Downstream sequence

AGTGGATTTTTCATTATTTCCAAAAATATTCTGCTTGCTCTTTCTGAATAAACTATAGAGAGAAACACAGGTTTCTCTTCAGGTGCCTTATTAAGTTTAA