Basic Information
VIS ID
TVIS44001129
Fusion event
HTLV-1-DAB1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
p32.2
Reference genome
GRCh37/hg19
Start
58459512/57993840 (Hg38)
End
58459512/57993840 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA1B
Target gene
DAB1
Nearest miRNA
hsa-mir-12136/Upstream/2768117; hsa-mir-101-1/Downstream/1739387;
Nearest TSS
ENST00000473358/Upstream/109755; ENST00000419596/Downstream/66299;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/568875, chr1-CpG: 87/Downstream/255760
Upstream sequence
TCATTGTACTGGCAGAAGCTGGAAATTGGCCTAGACCCTTATTCAAAGGTTTAGCTCGTTCCTTAGGTCAAAGAAAGTTCAGTTGCACTGGTTCCTACAA
Downstream sequence
TCCCAACCCCAGTAGAAAGAGGCATTTAGGCATTCattcattagtattttacaagtatctctggaggtcctacaatgtgccaggccctgtgctaagtgct
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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