VISDB Viral Integration Site DataBase

VIS ID

TVIS44001130

Fusion event

HTLV-1-DOCK7 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

Adult T-cell leukemia (ATL)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr1

Cytoband

p31.3

Reference genome

Start

End

63106966/62641295 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-30a-5p ; hsa-mir-21-5p ; hsa-mir-1307-3p ; hsa-mir-6083 ; hsa-mir-3924 ; hsa-mir-297 ; hsa-mir-190a-3p ; hsa-mir-6867-5p ; hsa-mir-223-5p ; hsa-mir-567 ; hsa-mir-511-3p ; hsa-mir-5011-5p ; hsa-mir-5584-3p ; hsa-mir-4699-3p ; hsa-mir-5585-3p ; hsa-mir-210-3p ; hsa-let-7g-3p ; hsa-let-7a-2-3p ; hsa-mir-3177-5p ; hsa-mir-3682-3p ; hsa-mir-1245b-3p ; hsa-mir-5683 ; hsa-mir-665 ; hsa-mir-887-5p ; hsa-mir-6780a-5p ; hsa-mir-6779-5p ; hsa-mir-3689c ; hsa-mir-3689b-3p ; hsa-mir-3689a-3p ; hsa-mir-30b-3p ; hsa-mir-1273h-5p ; hsa-mir-6788-5p ; hsa-mir-30c-2-3p ; hsa-mir-30c-1-3p ; hsa-mir-7977 ; hsa-mir-6799-5p ; hsa-mir-6883-5p ; hsa-mir-6785-5p ; hsa-mir-4728-5p ; hsa-mir-149-3p ; hsa-mir-7106-5p ; hsa-mir-7703 ; hsa-mir-6720-5p ; hsa-mir-6512-3p ; hsa-mir-196a-3p ; hsa-mir-4252 ; hsa-mir-6499-3p ; hsa-mir-4537 ; hsa-mir-5186 ; hsa-mir-6860 ; hsa-mir-612 ; hsa-mir-5189-5p ; hsa-mir-3187-5p ; hsa-mir-1285-3p ; hsa-mir-4793-3p ; hsa-mir-766-3p ; hsa-mir-939-3p ; hsa-mir-6849-3p ; hsa-mir-1273g-3p ; hsa-mir-759 ; hsa-mir-5586-3p ; hsa-mir-508-5p ; hsa-mir-4797-5p

Nearest miRNA

hsa-mir-12132/Upstream/562436; hsa-mir-101-1/Downstream/685630;

Nearest TSS

Nearest CpG islands

None/Target, chr1-CpG: 111/Upstream/203299, chr1-CpG: 111/Downstream/46414

Upstream sequence

ATAGACTCATGAGCTGTCTTTTCTTCCAGTAGTGGATCTTAGCTTTCTTCTTTCTCTTCTTCTCCATGGTGGCTGTCACTGCCTGGTACTTCCAGCCAAC

Downstream sequence

ACCATGAGCCAGGAGCCCCAGGTAGGCAAACTTTCTCACAGGCTTCAGGCACACAACCTTGAGGGCAGCAGGAACCACAGTCCACTTTTTGTCATAGGGG