Basic Information
VIS ID
TVIS44001133
Fusion event
HTLV-1-AFAP1L2 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr10
Cytoband
q25.3
Reference genome
End
116161275/114401516 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
Target gene
miRNAs that regulate target gene
Nearest miRNA
hsa-mir-107/Upstream/227337; hsa-mir-202/Downstream/2425972;
Nearest cancer related gene
AFAP1L2(TSG, No orient, 0)
Upstream sequence
TTATGAGAGTCATAAATATGTAAACACATAAGGATGGGAACCTTCTCAAAGCACCCTGTAGGATTTGGCCCCACATCCTGACATTTGCGAGAGCCTTACT
Downstream sequence
GCTTATACAACGCCAAAGAGATTCACATACAAGACATAGCCATTTTACCATCGCTATTTATGGCAACTCTCATAAAAGTGCCATCTCTCTAGGAAGGGAC
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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