Basic Information
VIS ID
TVIS44001136
Fusion event
HTLV-1-LOC105369438 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr11
Cytoband
q21
Reference genome
GRCh37/hg19
Start
94286385/94553219 (Hg38)
End
94286385/94553219 (Hg38)
Orient
+
Location type
Intronic
Target gene
LOC105369438
Nearest miRNA
hsa-mir-10392/Upstream/86639; hsa-let-7a-2/Downstream/1788219;
Nearest TSS
ENST00000527297/Upstream/7933; ENST00000545603/Downstream/14089;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/7472, chr11-CpG: 83/Downstream/187150
Nearby gene
FUT4(+3321) ;
Upstream sequence
ctaaaaaaatacaaaaaaattagctgggcatggtggcgtgcgcctgtagtcccagctacttgggaggctgaggcaggagaatcgcttgcacctgggaggc
Downstream sequence
agaggttgcagtgagccaagatcacgccatagcagtccagcctgagtgatagagcaagactctgtctcaaaaataaataaataaataaaataaaacacca
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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