Basic Information
VIS ID
TVIS44001150
Fusion event
HTLV-1-chr22 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr22
Cytoband
q11.1
Reference genome
GRCh37/hg19
Start
17437429/16956539 (Hg38)
End
17437429/16956539 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-let-7a-3/Downstream/807641;
Nearest TSS
ENST00000624155/Upstream/22536; ENST00000608373/Downstream/11844;
Nearest CpG islands
None/Target, chr22-CpG: 279/Upstream/258624, chr22-CpG: 66/Downstream/50845
Nearby gene
GAB4(-5398) ;
Upstream sequence
AGATTGCTGTGCTTCCCCTTCAATGCAGGAACTGCAAGATCCTGGGTGACATCACTGCCCCACTTGCTGGTGCCAGGCCAGGACTGTGGACTAGCACTGA
Downstream sequence
ACCAGCACTCTCTGGAGTGTCCCAGGAGAGCCGTCCCAACCACTGCTAAGCCCGCAAGGGTGCTGCCGCCTAGGCCCTATGGGAACTGCCCACACAGGTG
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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