Basic Information
VIS ID
TVIS44001167
Fusion event
HTLV-1-chr6 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr6
Cytoband
p21.1
Reference genome
GRCh37/hg19
Start
41018881/41051142 (Hg38)
End
41018881/41051142 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
FRA6H
Nearest miRNA
hsa-mir-1236/Upstream/1976761; hsa-mir-10398/Downstream/547581;
Nearest TSS
ENST00000381078/Upstream/8424; ENST00000244669/Downstream/2162;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/22640, chr6-CpG: 138/Downstream/21100
Nearby gene
APOBEC2(+2059) ;
Upstream sequence
atggagaccatcctggccacatggtgaaaccctgtctctactaaaattacaaaaattagctgggcctggtggcacatgccagtagtcccagctactttgg
Downstream sequence
aggctgaggcaggagaatcggttgaactcgggaggcggaggttgcagtgagccaagatcgtgccactgcactccagtctggtgacagagtgagactccat
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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