Basic Information
VIS ID
TVIS44001184
Fusion event
HTLV-1-IQGAP3 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
q22
Reference genome
GRCh37/hg19
Start
156541787/156571995 (Hg38)
End
156541787/156571995 (Hg38)
Orient
-
Location type
Intronic
Target gene
IQGAP3
miRNAs that regulate target gene
hsa-mir-1-3p
Nearest miRNA
hsa-mir-101-1/Upstream/151566; hsa-mir-1182/Downstream/364136;
Nearest TSS
ENST00000473358/Upstream/32530; ENST00000495690/Downstream/545;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/66467, chr1-CpG: 34/Downstream/312
Upstream sequence
aaaatgtggcccagggactaccttcctcacaatcacctggggtgagggaagaagcacagcagtgcttgttataaatgcagattatgggccccaaaccaga
Downstream sequence
ccttctggaactgaagctctgggacaggtcccaggaatctgcatctcaaacaagcttcccgggtaattTCACCCCCTGTTTGACAGGCATTGTCTGAAAG
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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