Basic Information
VIS ID
TVIS44001237
Fusion event
HTLV-1-ANGPTL6 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr19
Cytoband
p13.2
Reference genome
GRCh37/hg19
Start
10212169/10101493 (Hg38)
End
10212169/10101493 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA19B
Target gene
ANGPTL6
Nearest miRNA
hsa-mir-1227/Upstream/63080; hsa-let-7e/Downstream/128920;
Nearest TSS
ENST00000633603/Upstream/4895; ENST00000430370/Downstream/1166;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/4818, chr19-CpG: 62/Downstream/4643
Upstream sequence
AAAAATAAAATAAAgaataagggacactttcacaaagacctgatggaagagagagaagaggaagagcattccaggcagagagaacagcaggtgcaaaggc
Downstream sequence
ccggagattgcacccaagaaatggcagaaaggggccaggcacggtggctcacgcctgtaatcccagcactttgggaggccgaggcgggaggatcacctga
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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