Basic Information
VIS ID
TVIS44001257
Fusion event
HTLV-1-chr3 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr3
Cytoband
p25.2
Reference genome
GRCh37/hg19
Start
11986536/11945062 (Hg38)
End
11986536/11945062 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-12127/Upstream/1550500; hsa-let-7g/Downstream/3551177;
Nearest TSS
ENST00000440867/Upstream/98143; ENST00000424884/Downstream/59340;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/42603, chr3-CpG: 67/Downstream/59329
Nearby gene
SYN2(+59298) ;
Upstream sequence
agtgctcactaggtagctttttgattctcaccctcctcccaccctctactctcaagtaagctccagtgtctatgattcccttgtttgtgtctatccgtac
Downstream sequence
tcaatgtttagctccacttggaagtgagaacatgtggtatttggttttcttttcctgcattaatttgcttaggataattgcctctagctgcatccatgtt
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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