Basic Information
VIS ID
TVIS44001266
Fusion event
HTLV-1-RAB28 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr4
Cytoband
p15.33
Reference genome
GRCh37/hg19
Start
13420781/13419157 (Hg38)
End
13420781/13419157 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA4D
Target gene
RAB28
miRNAs that regulate target gene
hsa-mir-197-3p ; hsa-mir-375
Nearest miRNA
hsa-mir-12113/Upstream/1635909; hsa-mir-12115/Downstream/208708;
Nearest TSS
ENST00000502981/Upstream/37563; ENST00000510907/Downstream/55165;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/1989525, chr4-CpG: 97/Downstream/64741
Upstream sequence
ctgccaagtaaatgaaagcaaaaaaaagcaggggttgcaatcctagcctttgataaaacagacattaaaaaaacaaagatcaaaaaagacaaagaaggcc
Downstream sequence
attacataatggtaaagggatcaattcaacaaaaagagccagctatcctaaatatacatgcacgcaatacaggagcacccagattcataaagcaagtcct
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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