Basic Information
VIS ID
TVIS44001269
Fusion event
HTLV-1-chr4 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr4
Cytoband
q25
Reference genome
GRCh37/hg19
Start
111808481/110887325 (Hg38)
End
111808481/110887325 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-12113/Upstream/26678; hsa-mir-1243/Downstream/1760549;
Nearest TSS
ENST00000502981/Upstream/92922; ENST00000510034/Downstream/753170;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/247673, chr4-CpG: 120/Downstream/1257989
Nearby gene
PITX2(-245202) ;
Nearest cancer related gene
PITX2(OG, -245202) ;
Upstream sequence
TTTTATGTTTTAGAGTCTGTGTTTGGTGCTAGGTTAAATATTATTCTTTTCTTGCATTTCTCCATGAATATCTACTTGAGTTTTGAATTTGAACATATCC
Downstream sequence
AGTTTTTTAAAAAAATTAAAAGAGGAATATTTTGGAGGAGAAGGCAACTGCTTTTCATCTCAGTAAATTCAGAAAACAACACTAACGTGTTTTGTAAATA
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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