Basic Information
VIS ID
TVIS44001284
Fusion event
HTLV-1-LOC105374971 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr6
Cytoband
p22.3
Reference genome
GRCh37/hg19
Start
22470343/22470114 (Hg38)
End
22470343/22470114 (Hg38)
Orient
-
Location type
Intronic
Target gene
LOC105374971
Nearest miRNA
hsa-mir-3691/Upstream/3898234; hsa-mir-10398/Downstream/4677512;
Nearest TSS
ENST00000381078/Upstream/172613; ENST00000510882/Downstream/99379;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/803483, chr6-CpG: 100/Downstream/99241
Nearby gene
HDGFL1(+99335) ;
Upstream sequence
GCGAGTGACAAACTTTCCCAAAGAACCCACGGTAGTCTTTGCATCTATATACTTATACTAAAGTTTCCCAAATAATTAATAAGCATTTCTCACCCACAGG
Downstream sequence
TTACTCATCTTAGGGCTTAATTTGTAAAGCTTCTTGAAAGctttggtatccaaagtgtggctctaggcctacacggccactgcttagaagcatgttacaa
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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