Basic Information
VIS ID
TVIS44001299
Fusion event
HTLV-1-CLVS1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr8
Cytoband
q12.2
Reference genome
GRCh37/hg19
Start
61939777/61027218 (Hg38)
End
61939777/61027218 (Hg38)
Orient
-
Location type
Intronic
Target gene
CLVS1
miRNAs that regulate target gene
hsa-mir-215-5p ; hsa-mir-192-5p
Nearest miRNA
hsa-mir-124-1/Upstream/18130943; hsa-mir-10400/Downstream/687570;
Nearest TSS
ENST00000518652/Upstream/59443; ENST00000523868/Downstream/29940;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/103906, chr8-CpG: 66/Downstream/111869
Nearby gene
LOC100130298(-59470) ;
Upstream sequence
CATGCCTATCCCAATAGGGCGAAGAATGCATGAAGGAAATGAACATGATGGATCATATACATCATACTGTCATCCCCCAAGAGTGAGACAAACAGTATCT
Downstream sequence
TGAGGAGGCTCACACTGTCTTCCTGATAAAAGCCAACAAGAATGTGCATTAAAATGGATCCTGTATTTTATGATAAACTATTCTCGCCCTGTGTTATATT
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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