Basic Information
VIS ID
TVIS44001326
Fusion event
HTLV-1-LOC105371664 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
q31.2
Reference genome
GRCh37/hg19
Start
192495612/192526482 (Hg38)
End
192495612/192526482 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA1K
Target gene
LOC105371664
Nearest miRNA
hsa-mir-101-1/Upstream/12088092; hsa-mir-1182/Downstream/189846;
Nearest TSS
ENST00000473358/Upstream/9292; ENST00000457321/Downstream/3097;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/5845533, chr1-CpG: 56/Downstream/282020
Nearby gene
RGS1(+49245) ;
Upstream sequence
agtagagatggggtttcagcatgttggccaggctggtgtcaaactcctgacctcaggtgatccacccaccttggcctcccaaagtgctgggattacagga
Downstream sequence
atgagccactgcgcccggcccttgctgttctttttgtccagatgcacttccctgagatattgttataacttgcattatgacttttctcaggtctctgtta
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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