Basic Information
VIS ID
TVIS44001356
Fusion event
HTLV-1-MIR548W integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr17
Cytoband
q23.3
Reference genome
GRCh37/hg19
Start
61247173/63169812 (Hg38)
End
61247173/63169812 (Hg38)
Orient
+
Location type
ncRNA_intronic
Target gene
MIR548W
Nearest miRNA
hsa-mir-10226/Upstream/225500; hsa-mir-1250/Downstream/1330962;
Nearest TSS
ENST00000595228/Upstream/21584; ENST00000583545/Downstream/24182;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/202765, chr17-CpG: 19/Downstream/264480
Upstream sequence
ctgaggcaggagaatcacttgaacccgggaggcggagattacagtgagtcaagatcccgctattgcactccagcctggcaacaaagtgagactccatctc
Downstream sequence
aaaaaataataataataataataatTTTAAAAATTTATGGcaggtgcggaggctcacgcctgtaatcccagcactttgggaggccaaggcgggcagatca
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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