Basic Information
VIS ID
TVIS44001361
Fusion event
HTLV-1-chr19 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr19
Cytoband
q13.2
Reference genome
GRCh37/hg19
Start
43392136/42887984 (Hg38)
End
43392136/42887984 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
FRA19A
Nearest miRNA
hsa-mir-10395/Upstream/536779; hsa-let-7e/Downstream/1765702;
Nearest TSS
ENST00000633603/Upstream/8162; ENST00000635346/Downstream/22820;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/189823, chr19-CpG: 42/Downstream/520031
Nearby gene
PSG1(-8265) ;
Upstream sequence
TGGGTCATATGGAGAATTAGCAGTGGGAGACTAGAAATTAAAGTGGATAAAGGGAAGAATTAAAAGTCAAAAACAGTGTGAGGGAGGAAAGGAATGGATA
Downstream sequence
TAACACCTCACAGCTTTATCCTTGAGAGGCCTTAAAGAATCTACTTAATAATAATCAGATGGTATTCTATAAGAACTTTGAGACTAGACATGTGATGACT
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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