Basic Information
VIS ID
TVIS44001382
Fusion event
HTLV-1-ZNF717 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr3
Cytoband
p12.3
Reference genome
GRCh37/hg19
Start
75832119/75782968 (Hg38)
End
75832119/75782968 (Hg38)
Orient
+
Location type
Intronic
Target gene
ZNF717
Nearest miRNA
hsa-let-7g/Upstream/44605; hsa-mir-12124/Downstream/3724919;
Nearest TSS
ENST00000440867/Upstream/108555; ENST00000475034/Downstream/2090;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/110210, chr3-CpG: 48/Downstream/2135
Upstream sequence
ATGCCGTGCTTTAGCAGAAGATGACCGTTTCCACTGCACAACACTACAAGTATTTACTGCCAGGCTGGTGTGAAATATGTTCCAGCACATAACCTATGTC
Downstream sequence
ACCACCGAAGGTGGTGGTTCAGACTTGGTGCACACAAGCTTTCCTGTCCCACAAGAACACAGCATGCTCTCTTCGCGGGTTCCATTCCAATCACGTAACA
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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