Basic Information
VIS ID
TVIS44001383
Fusion event
HTLV-1-chr3 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr3
Cytoband
p12.3
Reference genome
GRCh37/hg19
Start
78466095/78416945 (Hg38)
End
78466095/78416945 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-let-7g/Upstream/2678582; hsa-mir-12124/Downstream/1090942;
Nearest TSS
ENST00000440867/Upstream/149939; ENST00000473938/Downstream/190344;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/1318697, chr3-CpG: 49/Downstream/601968
Nearby gene
ROBO1(-180293) ;
Nearest cancer related gene
ROBO1(TSG, -180293) ;
Upstream sequence
AAGGAGAATCTGAGACTGCACCCATACTCTGGAAACAACCAGTAAGCTTATGCAGCTACCCTGATCTctagatcattcttctttggttagaattaaaact
Downstream sequence
acatcattattttaactcacagcttttctatatatttttaatgagtgtattcacagaaaagaagagtatgaaatgtgctcttgcaaaatgagccactcag
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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