Basic Information
VIS ID
TVIS44001385
Fusion event
HTLV-1-STPG2 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr4
Cytoband
q22.3
Reference genome
GRCh37/hg19
Start
98625251/97704100 (Hg38)
End
98625251/97704100 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA4E
Target gene
STPG2
Nearest miRNA
hsa-mir-12113/Upstream/10403517; hsa-mir-1243/Downstream/1293287;
Nearest TSS
ENST00000502981/Upstream/337174; ENST00000503667/Downstream/189103;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/2154257, chr4-CpG: 19/Downstream/439351
Upstream sequence
taggctggtcttatcctttcacatttttctgcctgctttatattctagctgtgctggcagctgattagatggtacccacccagattaacggtgggtctgc
Downstream sequence
ctttccagcccactgactcaaatgttaatctcctttggcaacaccctaacagacacacccaggatcagtattttgaatactctgtatccttcaatccaat
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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