Basic Information
VIS ID
TVIS44001399
Fusion event
HTLV-1-C1QTNF3-AMACR integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr5
Cytoband
p13.2
Reference genome
GRCh37/hg19
Start
34051266/34051161 (Hg38)
End
34051266/34051161 (Hg38)
Orient
+
Location type
ncRNA_intronic
Fragile sites / regions
FRA5A
Target gene
C1QTNF3-AMACR
Nearest miRNA
hsa-mir-10397/Upstream/1656686; hsa-mir-103a-1/Downstream/2096731;
Nearest TSS
ENST00000502646/Upstream/7329; ENST00000607051/Downstream/73367;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/42933, chr5-CpG: 131/Downstream/604857
Upstream sequence
tgggaaggactccttactcctgaaaagggacatacagaaaggaaatgtacttcttctctctcttcttccactgaatatagtcatgtttacatacaaaatg
Downstream sequence
ggacactacagcaaaccctaggatagcagagcagaaagatggaaataacctggtcctagatggcatttgtgagccaccaaattacctaattgcccagtct
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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