VISDB Viral Integration Site DataBase

VIS ID

TVIS44001408

Fusion event

HTLV-1-TBPL1 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

Adult T-cell leukemia (ATL)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr6

Cytoband

q23.2

Reference genome

Start

End

134284385/133963247 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-9-5p ; hsa-mir-24-3p ; hsa-mir-424-5p ; hsa-mir-18a-5p ; hsa-mir-214-3p ; hsa-mir-18b-5p ; hsa-mir-657 ; hsa-mir-761 ; hsa-mir-1303 ; hsa-mir-3619-5p ; hsa-mir-3907 ; hsa-mir-3934-3p ; hsa-mir-3944-5p ; hsa-mir-4735-3p ; hsa-mir-6083 ; hsa-mir-15a-5p ; hsa-mir-16-5p ; hsa-mir-96-3p ; hsa-mir-15b-5p ; hsa-mir-195-5p ; hsa-mir-497-5p ; hsa-mir-548e-5p ; hsa-mir-2681-3p ; hsa-mir-3942-5p ; hsa-mir-4703-5p ; hsa-mir-6838-5p ; hsa-mir-431-5p ; hsa-mir-30a-5p ; hsa-mir-30c-5p ; hsa-mir-30d-5p ; hsa-mir-30b-5p ; hsa-mir-30e-5p ; hsa-mir-580-3p ; hsa-mir-6810-5p ; hsa-mir-935 ; hsa-mir-107 ; hsa-mir-103a-3p ; hsa-mir-1277-5p ; hsa-mir-448 ; hsa-mir-190a-3p ; hsa-mir-4789-5p ; hsa-mir-3941 ; hsa-mir-5011-5p ; hsa-mir-603 ; hsa-mir-362-3p ; hsa-mir-329-3p ; hsa-mir-8485 ; hsa-mir-143-5p ; hsa-mir-643 ; hsa-mir-4448 ; hsa-mir-3613-3p ; hsa-mir-3115 ; hsa-mir-4504 ; hsa-mir-4652-5p ; hsa-mir-3191-3p ; hsa-mir-3194-3p ; hsa-mir-3144-5p ; hsa-mir-8064 ; hsa-mir-2277-3p ; hsa-mir-6728-3p ; hsa-mir-6890-5p ; hsa-mir-3675-5p ; hsa-mir-542-3p

Nearest miRNA

hsa-mir-10398/Upstream/1847984; hsa-mir-1202/Downstream/1016091;

Nearest TSS

Nearest CpG islands

None/Target, chr6-CpG: 120/Upstream/9541, chr6-CpG: 111/Downstream/211554

Upstream sequence

CAAGGGATGGTAAACAGAATGTAGAAGTCTTGATGTTCTCTGAAAAACAGTACTGATAGAAGAATAGAGCCCTTTTTAAGGATTTATGGAGAGGGAAATT

Downstream sequence

CCATTATTTTAATTACCCTATGATGGTGTTTCAACCcagtcgttctcaactgactacccattagaaacatcttggaaatattttcaaaattagggcccta