Basic Information
VIS ID
TVIS44001420
Fusion event
HTLV-1-MSC-AS1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr8
Cytoband
q13.3
Reference genome
GRCh37/hg19
Start
72763536/71851301 (Hg38)
End
72763536/71851301 (Hg38)
Orient
+
Location type
ncRNA_intronic
Target gene
MSC-AS1
Nearest miRNA
hsa-mir-124-1/Upstream/7472044; hsa-mir-10400/Downstream/2697242;
Nearest TSS
ENST00000518652/Upstream/6833; ENST00000518700/Downstream/110633;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/6869, chr8-CpG: 29/Downstream/153769
Upstream sequence
ACCAACTCAGTGTATTACTATGTGTTCTACCCACTGATAGCAGTTATAAGGACTCTTTTACATTTCTTATTAACTGAATGGACTTCTAAGGAATATTTCC
Downstream sequence
TCTTATCAAATGGAGTATATATCTTTCTATTTATTATACACTGTGCTTGCCACAACGCCCAGAGGAAGTCTAAATAACTCAACAATTATATTTATTATAA
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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