Basic Information
VIS ID
TVIS44001432
Fusion event
HTLV-1-chr9 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr9
Cytoband
q33.1
Reference genome
GRCh37/hg19
Start
117903364/115141085 (Hg38)
End
117903364/115141085 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
FRA9E ; FRA9B
Nearest miRNA
hsa-let-7a-1/Upstream/931556; hsa-mir-12126/Downstream/5103894;
Nearest TSS
ENST00000422679/Upstream/2676; ENST00000477580/Downstream/733;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/529289, chr9-CpG: 77/Downstream/1012998
Nearby gene
DEC1(+733) ;
Nearest cancer related gene
DEC1(TSG, +733) ;
Upstream sequence
ATTTCCCCATGGAGGCAGCATTGTTATACAGGTGACAATGAGATAACAATGCAAAGAAACCAGAAGTCAAGTTCATATCGACTTATATAGCTCTGTCTCC
Downstream sequence
ATAAGTCAGAAACAGGAAAAATTAACTTGTTCTTCAGCAATCTAGGTTGACTTCATGAACGAGCTGGCGTTCAAATGAATCCTTgaattgtggaaacaga
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
Curate