Basic Information
VIS ID
TVIS44001446
Fusion event
HTLV-1-chr7 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr7
Cytoband
p11.2
Reference genome
GRCh37/hg19
Start
57462256/57394549 (Hg38)
End
57462256/57394549 (Hg38)
Orient
-
Location type
Intergenic
Fragile sites / regions
FRA7A
Nearest miRNA
hsa-mir-1183/Upstream/438685; hsa-mir-10399/Downstream/10476;
Nearest TSS
ENST00000635602/Upstream/172375; ENST00000563054/Downstream/10222;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/137381, chr7-CpG: 38/Downstream/10061
Nearby gene
MIR3147(+10475) ;
Upstream sequence
gcaaagactcaggtcctagaactcaggatttgtcttccagctggctctcctcattgactcaagatggctgctgctgctccagacatcacagcccttctct
Downstream sequence
aacaacacttgtgagataaaacctccctctccttttttcttttatctaagCACTCTCATAAATAATTTTTTTAAGTGTGGGCAGCATTGGAAACTGCACA
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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