VISDB Viral Integration Site DataBase

VIS ID

TVIS44001449

Fusion event

HTLV-1-ZNF716 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

Adult T-cell leukemia (ATL)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr7

Cytoband

p11.2

Reference genome

Start

End

57511386/57451680 (Hg38)

Orient

-

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-4279 ; hsa-mir-1200 ; hsa-mir-3649 ; hsa-mir-6829-3p ; hsa-mir-6791-3p ; hsa-mir-1976 ; hsa-mir-3653-5p ; hsa-mir-6747-3p ; hsa-mir-6727-3p ; hsa-mir-4722-3p ; hsa-mir-544b ; hsa-mir-4324 ; hsa-mir-660-3p ; hsa-mir-5571-5p ; hsa-mir-582-3p ; hsa-mir-4798-5p ; hsa-mir-7977 ; hsa-mir-383-3p ; hsa-mir-6514-3p ; hsa-mir-6811-3p ; hsa-mir-214-5p ; hsa-mir-1273e ; hsa-mir-6516-5p ; hsa-mir-455-3p ; hsa-mir-489-3p ; hsa-mir-650 ; hsa-mir-3612 ; hsa-mir-6499-3p ; hsa-mir-2467-3p ; hsa-mir-6086 ; hsa-mir-377-5p ; hsa-mir-4487 ; hsa-mir-558 ; hsa-mir-3160-3p ; hsa-mir-3913-3p ; hsa-mir-6719-3p ; hsa-mir-6840-3p ; hsa-mir-4257 ; hsa-mir-6511a-5p ; hsa-mir-1910-3p ; hsa-mir-1262 ; hsa-mir-3609 ; hsa-mir-3664-5p ; hsa-mir-3672 ; hsa-mir-4504 ; hsa-mir-4522 ; hsa-mir-4701-3p ; hsa-mir-508-5p ; hsa-mir-520g-3p ; hsa-mir-520h ; hsa-mir-548ah-5p ; hsa-mir-6510-3p ; hsa-mir-6512-3p ; hsa-mir-661 ; hsa-mir-6720-5p ; hsa-mir-6736-5p ; hsa-mir-6742-3p ; hsa-mir-6776-5p ; hsa-mir-6849-3p ; hsa-mir-6864-3p ; hsa-mir-766-3p ; hsa-mir-873-3p

Nearest miRNA

hsa-mir-1183/Upstream/46590; hsa-mir-10399/Downstream/6169410;

Nearest TSS

Nearest CpG islands

None/Target, chr7-CpG: 39/Upstream/26314, chr7-CpG: 22/Downstream/178031

Upstream sequence

gggattacatgcacccgccaccatgcctggctaatttttgtatttttagtagagatagagtgttgccatgctggccaggctggtctcaaactcctggcct

Downstream sequence

caagtgatctgcccacctttgtctctcaaagtgctgggattacaggaataggctatcacacccagcctgcgtttttcaactctttctttctttttttttt