Basic Information
VIS ID
TVIS44001456
Fusion event
HTLV-1-chr12 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr12
Cytoband
q24.32
Reference genome
GRCh37/hg19
Start
128699471/128214926 (Hg38)
End
128699471/128214926 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
FRA12E
Nearest miRNA
hsa-let-7i/Upstream/3299267; hsa-mir-3612/Downstream/79166;
Nearest TSS
ENST00000382841/Upstream/23537; ENST00000435159/Downstream/52477;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/453635, chr12-CpG: 196/Downstream/51570
Nearby gene
MIR4419B(+29580) ;
Upstream sequence
CCTGTTCCAAACATGTCGTTCCAACCTGTGGCAAAAGGTGTTGGCTCCAAACCCAAAATCCATCCCTCCCCTCAGAGTAGGTGACCTCATCTATGTCTAG
Downstream sequence
ATCAggggttaatccagaatactctaagccaatcatggtgtcccttgccccaccagtgtttggtttaggggtaggcatgtgacctgcatctgaccaacga
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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