Basic Information
VIS ID
TVIS44001457
Fusion event
HTLV-1-C2orf27A integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
q21.2
Reference genome
GRCh37/hg19
Start
132513623/131756050 (Hg38)
End
132513623/131756050 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA2S
Target gene
C2orf27A
Nearest miRNA
hsa-mir-1285-2/Upstream/264814; hsa-mir-10b/Downstream/500916;
Nearest TSS
ENST00000437798/Upstream/119025; ENST00000421696/Downstream/45611;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/73201, chr2-CpG: 71/Downstream/45336
Upstream sequence
ggacagaaggcccatgaggggaaggtgaggcacttgtggcagagaaaaagaaaaaccgccccgcggagaagcggggcctgggtcccccacggacgaaagt
Downstream sequence
gtccgtcagcccttgagctgggccccgaagacgctgacgtccctggttcgagcccacagtgcgcctcaggctgctaggagtaccccatggaggaaagaag
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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