Basic Information
VIS ID
TVIS44001471
Fusion event
HTLV-1-LOC105373576 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
q14.1
Reference genome
GRCh37/hg19
Start
117144374/116386798 (Hg38)
End
117144374/116386798 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA2S
Target gene
LOC105373576
Nearest miRNA
hsa-mir-1285-2/Upstream/2665430; hsa-mir-10b/Downstream/11036739;
Nearest TSS
ENST00000437798/Upstream/572135; ENST00000489933/Downstream/1417376;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/1223609, chr2-CpG: 48/Downstream/1427738
Nearby gene
DPP10(+542048) ;
Upstream sequence
AGTTCTCATGAGTTCTCTCTATTTACACTCAATGATAAGTCCCAAAATATTTCATCTAGATACAAGTTACATGAAAAAGGAGTCCATGTAAATGAATTGC
Downstream sequence
CCGCCTGaaaaaaattaaaaaaaaaaaaaCCGTATAAGAGTGAAGTGCCATTTGATAATCTACAGTAGAGATAGAAGTTTACAGTTAACATGCTTATATC
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
Curate