Basic Information
VIS ID
TVIS44001478
Fusion event
HTLV-1-chr12 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr12
Cytoband
p12.1
Reference genome
GRCh37/hg19
Start
25861347/25708413 (Hg38)
End
25861347/25708413 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-1244-3/Upstream/1495918; hsa-let-7i/Downstream/165607;
Nearest TSS
ENST00000382841/Upstream/59834; ENST00000538081/Downstream/105758;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/321923, chr12-CpG: 155/Downstream/249845
Nearby gene
LMNTD1(No orient, 59851)
Nearest cancer related gene
LMNTD1(TSG, No orient, 59851)
Upstream sequence
tgtaaagcctgcagaaccatgagtcaattaaacctcttttctttataaattacccagtcttgggcatttcttgataacaatgcaacaatagcttaataca
Downstream sequence
ACTTCCATCCTGGTCCACACATAAATTACCTCTTAACCTATATCCCTTTATCAGATCCTTCCTTCAGCCCATCCAACAAGAAACAATCAAATAAGTCTTC
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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