Basic Information
VIS ID
TVIS44001524
Fusion event
HTLV-1-chr7 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr7
Cytoband
q11.23
Reference genome
GRCh37/hg19
Start
73670847/74256517 (Hg38)
End
73670847/74256517 (Hg38)
Orient
-
Location type
Intergenic
Fragile sites / regions
FRA7J
Nearest miRNA
hsa-mir-1183/Upstream/65223; hsa-mir-10399/Downstream/339451;
Nearest TSS
ENST00000635602/Upstream/2059; ENST00000487091/Downstream/32958;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/1705, chr7-CpG: 39/Downstream/32966
Nearby gene
RFC2(-2059) ;
Upstream sequence
TTCCTTTCATAATTCTCCAAAAACCCCCACTCTACAGGAGGCCTTTTGGCGCTGCTAGGGCTCTCCTCTAACTGATGGAATGCCAGGAGAACCAGAGATG
Downstream sequence
GAGGTGACTCTTAGGGCAAAGCTGCACTGTCAGGACATTTCTTTTTTTTAGACTGAGCCTTTTGTGACCTATTGGACTTGGGCCCAAACAGAGCTCAGAA
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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