Basic Information
VIS ID
TVIS44001526
Fusion event
HTLV-1-WDR95P integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr13
Cytoband
q12.3
Reference genome
GRCh37/hg19
Start
31682433/31108296 (Hg38)
End
31682433/31108296 (Hg38)
Orient
+
Location type
Intronic
Target gene
WDR95P
Nearest miRNA
hsa-mir-2276/Upstream/6945792; hsa-mir-1267/Downstream/8555738;
Nearest TSS
ENST00000623511/Upstream/112158; ENST00000461652/Downstream/30272;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/201328, chr13-CpG: 117/Downstream/52676
Nearby gene
HSPH1(-26678) ;
Upstream sequence
GATACTGGGCTGAAGAGCAAGGCAGCAGCCACATCTCCATATAGGTGACCCTCCATCCTGCCTCTGAGAGCATTCAGCCCCCTAAGGACAATCACAAAGG
Downstream sequence
ATAACGTCaagggcatgggctttggaggcaaacagctggggttgaatcccaacccctccattagtagctgtgtttgtgggcacattatggttccttctaa
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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