Basic Information
VIS ID
TVIS44001543
Fusion event
HTLV-1-MOGAT2 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr11
Cytoband
q13.5
Reference genome
GRCh37/hg19
Start
75436055/75725010 (Hg38)
End
75436055/75725010 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA11H
Target gene
MOGAT2
Nearest miRNA
hsa-mir-10392/Upstream/389824; hsa-let-7a-2/Downstream/3677012;
Nearest TSS
ENST00000527297/Upstream/5636; ENST00000624180/Downstream/5993;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/56173, chr11-CpG: 84/Downstream/43407
Upstream sequence
ctgtacttctctatggtgacacaacggtccattgtgtggatgtttcacaaattgtctaaataggccctgctgatggtcatttaagtggatgacaaatttt
Downstream sequence
tcatatcaccaaaacctgatgcttctgtgaataaccttgttcaggtgtcattttgcacaagtgtgagaaattctgtaggctaaattcctcagcagtggag
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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