Basic Information
VIS ID
TVIS44001549
Fusion event
HTLV-1-LOC105369165 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
p16.2
Reference genome
GRCh37/hg19
Start
53200705/52973567 (Hg38)
End
53200705/52973567 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA2S ; FRA2D ; FRA2H
Target gene
LOC105369165
Nearest miRNA
hsa-mir-1301/Upstream/270952; hsa-mir-10b/Downstream/875555;
Nearest TSS
ENST00000437798/Upstream/63547; ENST00000295304/Downstream/632511;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/343581, chr2-CpG: 28/Downstream/794187
Nearby gene
MIR4431(-270952) ;
Upstream sequence
ATTGAAAAACTGGAAGATCTCTAAACAGAAAAACTAATCATATTATAGTCTTACTTCTtgatatgatttggatccgtgtccccaccaaatctcatgttga
Downstream sequence
attgtaatcccccgtgttgaaggtgggccctggtgggaggtgattggatcatgggggtagagttctcatgaatagtttagcaccatcacccttggtcaca
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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