Basic Information
VIS ID
TVIS44001575
Fusion event
HTLV-1-chr18 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr18
Cytoband
q21.32
Reference genome
GRCh37/hg19
Start
57591922/59924690 (Hg38)
End
57591922/59924690 (Hg38)
Orient
-
Location type
Intergenic
Fragile sites / regions
FRA18B
Nearest miRNA
hsa-mir-1-2/Upstream/1473532; hsa-mir-5011/Downstream/7156894;
Nearest TSS
ENST00000575820/Upstream/24654; ENST00000585691/Downstream/85591;
Nearest CpG islands
None/Target, chr18-CpG: 67/Upstream/24199, chr18-CpG: 59/Downstream/44747
Nearby gene
PMAIP1(+20384) ;
Upstream sequence
GTACTCTTTCTCCTCACCAGAAGTCAGTATATTAAAACCTGATTTAATTAGATACACTCAACAGGGGATGGTTGAGCTTTCTTTCATttcgtcagtgtag
Downstream sequence
gattctgttataaataatcccaaaatagaagttgtttaacaaaattaaaagttcatgggttgctcacaaaaagtctaatgctgttgttcctagttgagag
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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