Basic Information
VIS ID
TVIS44001587
Fusion event
HTLV-1-chr15 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr15
Cytoband
q22.31
Reference genome
GRCh37/hg19
Start
64146183/63853984 (Hg38)
End
64146183/63853984 (Hg38)
Orient
-
Location type
Intergenic
Fragile sites / regions
FRA15A
Nearest miRNA
hsa-mir-10393/Upstream/1029943; hsa-mir-11181/Downstream/16946;
Nearest TSS
ENST00000557528/Upstream/20042; ENST00000558050/Downstream/57959;
Nearest CpG islands
None/Target, chr15-CpG: 55/Upstream/19518, chr15-CpG: 72/Downstream/191969
Nearby gene
MIR422A(-16946) ;
Nearest cancer related gene
MIR422A(TSG, -16946) ;
Upstream sequence
ccaaggccaaagaaccccttgagcccaggagtttgagactgcagtgagctgtaatcaggccacaacagtccaacctgggtaacacagcaagaccctgtct
Downstream sequence
ccaaaaaggaaagaaaatgtggtacatatacaccatggaatactacacagccataaaaagaatgaaatcatgtcctttgcagcaacgtggatgaggctgg
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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