Basic Information
VIS ID
TVIS44001592
Fusion event
HTLV-1-SPATA6L integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr9
Cytoband
p24.1
Reference genome
GRCh37/hg19
Start
4650557/4650557 (Hg38)
End
4650557/4650557 (Hg38)
Orient
-
Location type
Intronic
Target gene
SPATA6L
miRNAs that regulate target gene
hsa-mir-335-5p
Nearest miRNA
hsa-mir-1302-9/Upstream/4620276; hsa-let-7a-1/Downstream/199740;
Nearest TSS
ENST00000422679/Upstream/78222; ENST00000381883/Downstream/11758;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/159139, chr9-CpG: 66/Downstream/11695
Upstream sequence
ataaagattaagcagaaagtaatgaaatagaaaacagaaaagcaacacagaaaatcaatacatctaaaagttggttgtttaaaatgatcaataaaactga
Downstream sequence
caaacctttagctacactaaccaagaaaaaagagaaaagactcaaattactaaaatcagaaatgaaagaagagacattaccactgattttacagaaataa
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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