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TVIS44001598
Basic Information
VIS ID
TVIS44001598
Fusion event
HTLV-1-CAPRIN2 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr12
Cytoband
p11.21
Reference genome
GRCh37/hg19
Start
30902793/30749859 (Hg38)
End
30902793/30749859 (Hg38)
Orient
-
Location type
Intronic
Target gene
CAPRIN2
miRNAs that regulate target gene
hsa-mir-124-3p
;
hsa-mir-340-5p
;
hsa-mir-93-5p
;
hsa-let-7f-5p
;
hsa-mir-20a-5p
;
hsa-mir-106b-5p
;
hsa-mir-759
;
hsa-mir-555
;
hsa-mir-4477b
;
hsa-mir-3159
;
hsa-mir-582-5p
;
hsa-mir-338-5p
;
hsa-mir-520e
;
hsa-mir-520d-3p
;
hsa-mir-520c-3p
;
hsa-mir-520b
;
hsa-mir-520a-3p
;
hsa-mir-373-3p
;
hsa-mir-372-3p
;
hsa-mir-302e
;
hsa-mir-302d-3p
;
hsa-mir-302c-3p
;
hsa-mir-302b-3p
;
hsa-mir-302a-3p
;
hsa-mir-519c-3p
;
hsa-mir-519b-3p
;
hsa-mir-519a-3p
;
hsa-mir-541-5p
;
hsa-mir-655-3p
;
hsa-mir-374c-5p
;
hsa-mir-130a-3p
;
hsa-mir-130b-3p
;
hsa-mir-301a-3p
;
hsa-mir-301b-3p
;
hsa-mir-3666
;
hsa-mir-4295
;
hsa-mir-454-3p
;
hsa-mir-19a-3p
;
hsa-mir-19b-3p
;
hsa-mir-181c-5p
;
hsa-mir-181d-5p
;
hsa-mir-4262
;
hsa-mir-181a-5p
;
hsa-mir-181b-5p
;
hsa-mir-4473
;
hsa-mir-4671-3p
;
hsa-mir-5590-3p
;
hsa-mir-616-3p
;
hsa-mir-142-5p
;
hsa-mir-520f-3p
;
hsa-mir-512-3p
;
hsa-mir-499b-3p
;
hsa-mir-499a-3p
;
hsa-mir-4796-3p
;
hsa-mir-548ah-5p
;
hsa-mir-3609
;
hsa-mir-106a-5p
;
hsa-mir-17-5p
;
hsa-mir-526b-3p
;
hsa-mir-519d-3p
;
hsa-mir-20b-5p
Nearest miRNA
hsa-mir-1244-3/Upstream/4875780; hsa-let-7i/Downstream/11573841;
Nearest TSS
ENST00000382841/Upstream/14712;
ENST00000500076/Downstream/1265;
Nearest CpG islands
None/Target,
chr12-CpG: 104/Upstream/53777
,
chr12-CpG: 70/Downstream/4566
Upstream sequence
tctgttggcaatataaattgggcagctgtcagagtatTACTCCAGATATCAAAGTTCATACATTTATTATAGAAGCAACATGTGGCTATAAAGACAGTAA
Downstream sequence
TGAAATACTGAGAATGAAGTTTGCCTGGCTGGAGCAATGAAATATAGCATGTCTTTAACATTTCTTAGAGAGCTACCATGGGAACAATCAATCTCCAACC
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
Sample Information
×
Sample name
ATL11-CR2
Sample type
Nontumor
Age
27
Gender
Male
CpG Island Information
×
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