Basic Information
VIS ID
TVIS44001611
Fusion event
HTLV-1-LOC112268446 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr3
Cytoband
q13.2
Reference genome
GRCh37/hg19
Start
112173648/112454801 (Hg38)
End
112173648/112454801 (Hg38)
Orient
-
Location type
Intronic
Target gene
LOC112268446
Nearest miRNA
hsa-let-7g/Upstream/341903; hsa-mir-12124/Downstream/282288;
Nearest TSS
ENST00000440867/Upstream/45667; ENST00000468642/Downstream/15221;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/121242, chr3-CpG: 77/Downstream/106374
Nearby gene
BTLA(-9165) ;
Upstream sequence
CTCCAGGAAATTGGGCTGACCAGAATAAATAGGAAAATAGCCCACAGAGAGGTGACCAAAATAATAAGGCAGGGCCCTCTTCCCGCTATTCCCAGGGTCA
Downstream sequence
GAAGTGAGAGTGGGTGGAAGGAGAAATGTTTTGTAACCAAAGGATATGGGCAAATTGGCTTTTCAGAGTACAATATTTTGACAGACTACTGCCTCTATTG
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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