Basic Information
VIS ID
TVIS44001634
Fusion event
HTLV-1-ZBED5-AS1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr11
Cytoband
p15.4
Reference genome
GRCh37/hg19
Start
10886612/10865065 (Hg38)
End
10886612/10865065 (Hg38)
Orient
+
Location type
ncRNA_intronic
Target gene
ZBED5-AS1
Nearest miRNA
hsa-mir-210/Upstream/356739; hsa-let-7a-2/Downstream/791586;
Nearest TSS
ENST00000527297/Upstream/6269; ENST00000530344/Downstream/196;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/6159, chr11-CpG: 86/Downstream/65738
Upstream sequence
gtattttggaattatagccttgcctcaaaggtgtgctctgtgattaaatgaacttctatttgtaaatcttgtttaaaTTTCTCTGATGAAAGGCATATCA
Downstream sequence
GTGTTGATAGCTGTGGAGGATAAGAACGCTGACAATAATAATGAGTACGATAATATCAGTGCCTTGGATTTATGCAGTATCATTACTTCGGGGCTTTGCG
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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