Basic Information
VIS ID
TVIS44001640
Fusion event
HTLV-1-FRG2HP integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr16
Cytoband
p11.1
Reference genome
GRCh37/hg19
Start
34570993/35336622 (Hg38)
End
34570993/35336622 (Hg38)
Orient
+
Location type
Intronic
Target gene
FRG2HP
Nearest miRNA
hsa-mir-1225/Upstream/1172949; hsa-mir-11401/Downstream/14955994;
Nearest TSS
ENST00000527434/Upstream/128663; ENST00000561756/Downstream/26790;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/128619, chr16-CpG: 38/Downstream/15724
Nearby gene
LINC01566(No orient, 26794)
Upstream sequence
TGAATCAGTCTTTCAAGTGAAGCTGTTCTGCCAGTGTCATGAGTGAATACATTTCTCAAAGTCTCCTCAGAGATCTAAGCCATTTCCCATTCCCAATTTC
Downstream sequence
AAAATAAAACCCTATCAAAGACACATAGCTCAGTATCTCTGATTCCAACCCTCCCTGGAGACTTCATAGGAACAGCCCAAGGCCTTACCTGCCTTTGCAT
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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