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TVIS44001645
Basic Information
VIS ID
TVIS44001645
Fusion event
HTLV-1-RAB1B integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr11
Cytoband
q13.2
Reference genome
GRCh37/hg19
Start
66039910/66272439 (Hg38)
End
66039910/66272439 (Hg38)
Orient
-
Location type
Exonic
Fragile sites / regions
FRA11H
Target gene
RAB1B
miRNAs that regulate target gene
hsa-mir-107
;
hsa-mir-130b-3p
;
hsa-mir-148a-3p
;
hsa-mir-103a-3p
;
hsa-mir-16-5p
;
hsa-mir-877-5p
;
hsa-mir-874-3p
;
hsa-mir-324-5p
;
hsa-mir-185-5p
;
hsa-mir-15b-5p
;
hsa-mir-502-5p
;
hsa-mir-1233-5p
;
hsa-mir-1249-5p
;
hsa-mir-1273h-5p
;
hsa-mir-1302
;
hsa-mir-148b-3p
;
hsa-mir-149-3p
;
hsa-mir-152-3p
;
hsa-mir-1825
;
hsa-mir-1910-3p
;
hsa-mir-214-3p
;
hsa-mir-30b-3p
;
hsa-mir-3126-5p
;
hsa-mir-3130-5p
;
hsa-mir-31-5p
;
hsa-mir-3185
;
hsa-mir-3619-5p
;
hsa-mir-3689a-3p
;
hsa-mir-3689b-3p
;
hsa-mir-3689c
;
hsa-mir-3925-5p
;
hsa-mir-3944-5p
;
hsa-mir-4298
;
hsa-mir-4306
;
hsa-mir-4428
;
hsa-mir-4436b-3p
;
hsa-mir-4482-5p
;
hsa-mir-4514
;
hsa-mir-4524a-3p
;
hsa-mir-4640-5p
;
hsa-mir-4644
;
hsa-mir-4648
;
hsa-mir-4651
;
hsa-mir-4690-5p
;
hsa-mir-4692
;
hsa-mir-4726-5p
;
hsa-mir-4728-5p
;
hsa-mir-4742-5p
;
hsa-mir-4802-3p
;
hsa-mir-552-3p
;
hsa-mir-5689
;
hsa-mir-589-5p
;
hsa-mir-608
;
hsa-mir-6165
;
hsa-mir-6508-3p
;
hsa-mir-6511a-5p
;
hsa-mir-6751-5p
;
hsa-mir-6752-5p
;
hsa-mir-6756-5p
;
hsa-mir-6766-5p
;
hsa-mir-6778-5p
;
hsa-mir-6779-5p
;
hsa-mir-6780a-5p
;
hsa-mir-6785-5p
;
hsa-mir-6797-5p
;
hsa-mir-6799-5p
;
hsa-mir-6803-5p
;
hsa-mir-6835-5p
;
hsa-mir-6842-5p
;
hsa-mir-6875-5p
;
hsa-mir-6883-5p
;
hsa-mir-7106-5p
;
hsa-mir-7110-5p
;
hsa-mir-761
;
hsa-mir-7845-5p
;
hsa-mir-873-5p
;
hsa-mir-942-3p
Nearest miRNA
hsa-mir-10392/Upstream/623186; hsa-let-7a-2/Downstream/661995;
Nearest TSS
ENST00000527297/Upstream/3849;
ENST00000534826/Downstream/5048;
Nearest CpG islands
None/Target,
chr11-CpG: 30/Upstream/3102
,
chr11-CpG: 97/Downstream/5301
Upstream sequence
TGCTCCTCTGCCTACTGTCTCCTAGTGGGACACAGCGGGCCAGGAACGGTTCCGGACCATCACTTCCAGCTACTACCGGGGGGCTCATGGCATCATCGTG
Downstream sequence
GTGTATGACGTCACTGACCAGGTACTCCTGGACTAGCCATCCTCAGCTTGGCCTCCTTAGCCTTAGGTCTTTGACTCTTCTTTTTCCTCCTTCCATCCTC
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
Sample Information
×
Sample name
ATL11-CR2
Sample type
Nontumor
Age
27
Gender
Male
CpG Island Information
×
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