Basic Information
VIS ID
TVIS44001661
Fusion event
HTLV-1-FOXP1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr3
Cytoband
p13
Reference genome
End
71625057/71575906 (Hg38)
Orient
+
Location type
Intronic
Target gene
Nearest miRNA
hsa-let-7g/Upstream/33817; hsa-mir-12124/Downstream/3638570;
Nearest cancer related gene
FOXP1(OG, No orient, 0)
Upstream sequence
AAGCAGGGAACCTGGAGCAGAGAAAGTCACATTATGACTCAATTGCACAGCTGGGAGGGAGAAAGGACACCTCGGAAATTCAGTTTGATGCTAGAAATAT
Downstream sequence
TCTTCAGTGTCCTAGTAAACAAAGTGAATCACAAAATTAGCTAAAATCAGAGCATCTGGTAAAATGTGGATGTCCACCTGACTTACAAGTAATAAATAAA
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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