Basic Information
VIS ID
TVIS44001678
Fusion event
HTLV-1-LANCL2 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr7
Cytoband
p11.2
Reference genome
GRCh37/hg19
Start
55455378/55387685 (Hg38)
End
55455378/55387685 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA7A
Target gene
LANCL2
miRNAs that regulate target gene
hsa-mir-218-5p
Nearest miRNA
hsa-mir-1183/Upstream/10505885; hsa-mir-10399/Downstream/1568100;
Nearest TSS
ENST00000635602/Upstream/21574; ENST00000486376/Downstream/6384;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/21107, chr7-CpG: 47/Downstream/61493
Upstream sequence
tttgcagttttattaagagcagattaataccttaagaaaaccttgttttaacatagaggattaatgttacaaagactatcctaaataattttttaaaatt
Downstream sequence
ataaccaacttaattacatacaaaattccttttataaattctccttcatgaaccttttcatgacttacacagaccgtttatgacatacttggactttgac
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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