Basic Information
VIS ID
TVIS44001683
Fusion event
HTLV-1-chr14 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr14
Cytoband
q12
Reference genome
GRCh37/hg19
Start
28924972/28455766 (Hg38)
End
28924972/28455766 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-208a/Upstream/822488; hsa-mir-1185-1/Downstream/2558880;
Nearest TSS
ENST00000550708/Upstream/137625; ENST00000637351/Downstream/157857;
Nearest CpG islands
None/Target, chr14-CpG: 35/Upstream/2250494, chr14-CpG: 203/Downstream/309917
Nearby gene
FOXG1-AS1(No orient, 269476)
Upstream sequence
TCCTAATGGCTGGGTGGTAATATTAAGATGGTGTATAATGAGAGAAGTGGGAAAGTGGGGAGGAGAGAAAGTACAAAATAAAGGACCTTCTTTTCTCTTC
Downstream sequence
CTTATAGCTACTACACCTCTGCTGTACACTCCTCACTCACCCCACAGGCAAAGCAGCAAGGTGTCAGTATTTAGGATTCATGTTAAGATCTGTTTTTACA
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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